Sources
Every page on this site links to the documents below. Each entry shows its publisher and dates, including the day we last checked the link.
67 sources. Preprints and aggregated test data carry a label because nobody has peer-reviewed them.
Regulators
- Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks
FDA says BPC-157 may pose immunogenicity and peptide impurity risks, and lists BPC-157 and TB-500 as previously on its safety-risk list after their nominations were withdrawn.
- FDA’s Concerns with Unapproved GLP-1 Drugs Used for Weight Loss
FDA says firms illegally sold unapproved GLP-1 drugs, including retatrutide, falsely labeled "for research purposes" or "not for human consumption."
- Gram Peptides - 721806 - 03/31/2026
FDA found that the company's retatrutide and tirzepatide, labeled "Research Use Only," were drugs for human use, citing its own site claims about reducing body weight.
- MHRA smashes major illicit weight loss medicine production facility in record seizure
MHRA seized more than 2,000 unlicensed retatrutide and tirzepatide pens at an illicit Northampton production facility and notes retatrutide has not been approved for UK use.
- Peptide Partners LLC - 735063 - 08/24/2026
FDA says the company's "research use only" products, including one sold as "GLP-3 Reta," are drugs for human use, and that selling bacteriostatic water provides the means to prepare an injectable drug.
- Royal Peptides LLC - 734884 - 08/24/2026
FDA says the company marketed bacteriostatic water alongside a "peptide guide" and "peptide calculator," which together provide the means to prepare an injectable drug.
- Think twice before injecting peptides bought online: unauthorized products can seriously harm you
Health Canada lists BPC-157, TB-500 and retatrutide among seized unauthorized injectable peptides and says "research use only" labels do not make them legal.
- Unapproved peptide product promoters and suppliers are put on notice
TGA warns that unapproved peptides may contain the wrong ingredients, be contaminated or fail sterility standards, and says labeling a blank vial counts as manufacture.
Studies and preprints
- Bypassing Prescribers and Pharmacists: Online Purchasing of Semaglutide and Tirzepatide “For Research Purposes” Editorial
38 sites sold semaglutide or tirzepatide "for research purposes"; 4 asked buyers to check a researcher box, none required proof of age, 37 said "not for human consumption," and 17 served targeted ads.
- Evaluation of Research Grade Peptides Marketed Directly to Consumers Reveals Extensive Variability in Purity and Measured Abundance Not peer-reviewed
A preprint of 6,441 Finnrick-tested samples across 14 peptides finds 41.6% to 71.1% failed basic quality criteria, and 15% of 243 endotoxin-tested samples had measurable endotoxin.
- Multifactor Quality and Safety Analysis of Semaglutide Products Sold by Online Sellers Without a Prescription: Market Surveillance, Content Analysis, and Product Purchase Evaluation Study
Of 317 online pharmacy links, 134 led to 59 illegal sites; test vials were 7.7% to 14.37% pure, held 28.56% to 38.69% more semaglutide than labeled, and all had endotoxin.
- Reference Standards to Support Quality of Synthetic Peptide Therapeutics
The authors write that peptide identity is typically confirmed with several orthogonal methods, including HPLC retention time, NMR, and mass spectrometry, separate from impurity and content tests.
- Safety and Risk Assessment of No-Prescription Online Semaglutide Purchases
Only 3 of 6 semaglutide orders arrived, scam sellers sought $650 to $1,200 more, and vials tested 7% to 14% pure vs 99% claimed with 29% to 39% extra drug; one had elevated endotoxin (8.95 EU/mg).
Drugmaker statements
- Identify Real Lilly Medicine
Lilly warns that illicit retatrutide, often sold under a "research use only" pretext, may contain harmful contaminants, impurities, or the wrong ingredients entirely.
- Lilly calls on online platforms, payment companies and regulators to shut down the illegal retatrutide black market
Lilly says no retatrutide medicine is approved anywhere; it filed six new lawsuits, referred 200+ parties to authorities, and reported 14,000+ sites, ads, posts and listings in 100+ countries.
- Lilly's triple agonist, retatrutide, successful in two additional Phase 3 obesity trials, delivering significant improvements in weight and A1C
Lilly reports two more successful Phase 3 retatrutide obesity trials and says it plans to submit a Biologics License Application to FDA in Q1 2027.
- What to know about retatrutide: An investigational triple hormone receptor agonist
Lilly states that no regulatory agency has approved retatrutide and that it is legally available only through Lilly's clinical trials.
Laws and lab standards
- § 201.128 Meaning of “intended uses”.
FDA rules tie intended use to the objective intent of those who label a product, which labeling claims, advertising matter, or oral or written statements can show.
- § 211.84 Testing and approval or rejection of components, drug product containers, and closures.
FDA's drug GMP rule requires at least one identity test on each component and lets a maker rely on a supplier's report only if it runs a specific identity test and validates the supplier's results.
- <71> Sterility Tests
The 2008 harmonized USP <71> text says its tests are not by themselves designed to ensure a batch is sterile, a pass covers only the sample examined, and incubation lasts at least 14 days.
- <85> Bacterial Endotoxins
USP says the Pharmacopeial Discussion Group approved the <85> Bacterial Endotoxins Test as a harmonized standard, official in USP since December 1, 2012.
- Counterfeit certificates and false claims of UKAS accreditation
UKAS warns of counterfeit certificates and organizations falsely claiming UKAS accreditation for management systems certification, and names the ones it knows about.
- Directory of Accredited Organizations
ANAB's directory searches accredited organizations by keyword, company, or certificate number and filters by status, including active, suspended, and withdrawn.
- False Claims of Accreditation
IAS names organizations that misuse its accreditation mark, including one issuing IAS-marked certificates without ever being accredited, and asks users to check its directory.
- Frequently Asked Questions
A2LA says a scope of accreditation lists the specific tests a lab was found competent to perform, and capabilities not listed on the scope are not covered by its accreditation.
- ILAC MRA Signatory Search
ILAC's search finds accreditation bodies that signed the ILAC Mutual Recognition Arrangement, by economy and scope, and links to some of their online directories.
- ISO/IEC 17025 — Testing and calibration laboratories
ISO says ISO/IEC 17025 enables laboratories to show they operate competently and generate valid results, and the current edition is ISO/IEC 17025:2017.
- Pyrogen and Endotoxins Testing: Questions and Answers
FDA's March 2026 revised guidance says USP <85>, USP <161>, and AAMI ST72 recommend testing components and finished products for pyrogens and endotoxins.
- Q7 Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients Guidance for Industry
ICH Q7 says a COA should list product name, batch, release and expiry or retest dates, each test's limits and numerical results, a dated quality signature, and the original maker's contact details.
- Search A2LA Directory of Accredited Organizations
A2LA's directory searches accredited organizations by name, certificate number, scope, or test method and links to suspended, withdrawn, and inactive certificates and false accreditation claims.
- Search UKAS accredited organisations
UKAS lets anyone browse its directory of accredited organizations and search by type, name, region, or category.
- Specifications: Test Procedures and Acceptance Criteria for New Drug Substances and New Drug Products: Chemical Substances Q6A
ICH Q6A says identification solely by a single chromatographic retention time is not specific, and the guideline does not adequately cover higher molecular weight peptides.
Consumer protection and lookup tools
- Corporate Registration
NASS links to each state and territory's business registration pages and corporate name databases through one drop-down menu.
- Domain Registration Data: Advanced Lookup Functionality Now Available
ICANN says it built its lookup tool as a free public service that shows public registration data, such as the date a domain name was registered.
- Federal Trade Commission Announces Final Rule Banning Fake Reviews and Testimonials
The FTC's final rule, approved 5-0, bans fake reviews such as AI-generated ones, undisclosed insider reviews, and buying or selling fake social media followers or views.
- FTC's Endorsement Guides: What People Are Asking
FTC says an influencer's personal discount code probably conveys a relationship with the brand, and shoppers may not understand that "affiliate link" means the poster gets paid.
- How to avoid an online shopping scam this holiday season
FTC warns that if a seller says you can only pay with a gift card, wire transfer, payment app, or cryptocurrency, it's probably a scam.
- ICANN Lookup
ICANN Lookup shows the current registration data for a domain name, pulled in real time from registries and registrars through RDAP.
- ICANN Update: Launching RDAP; Sunsetting WHOIS
ICANN says RDAP became the definitive source for generic top-level domain registration data on January 28, 2025, in place of the retired WHOIS services.
- Internet Crime Complaint Center (IC3)
The FBI runs the Internet Crime Complaint Center, which it calls the central hub for reporting cyber-enabled crime.
- Online Shopping
FTC says to search a company's name plus "complaint" or "scam," warns that some reviews are fake, and says never to pay sellers who insist on gift cards, wire transfers, payment apps, or crypto.
- OpenCorporates
OpenCorporates says its company data comes direct from official primary sources across 140+ jurisdictions.
- ReportFraud.ftc.gov
The FTC's ReportFraud.ftc.gov takes reports of fraud, scams, and bad business practices and shares them with over 2,000 law enforcers, but it does not resolve individual reports.
- The Consumer Reviews and Testimonials Rule: Questions and Answers
FTC says its Rule on the Use of Consumer Reviews and Testimonials took effect October 21, 2024, and lets courts impose civil penalties for knowing violations.
- Using Credit Cards and Disputing Charges
FTC says a Fair Credit Billing Act dispute letter must reach the card issuer within 60 days after the first bill with the error, and federal law caps unauthorized charges at $50.
- What To Do if You Were Scammed
FTC says cryptocurrency payments lack the legal protections of credit and debit cards, so money is hard to get back, and it takes scam reports at ReportFraud.ftc.gov.
Independent data and reporting
- Methodology
Finnrick says it sources samples from vendors and sends them to third-party labs, requests HPLC as the primary method, and does not require endotoxin testing.
- Retatrutide Safety Testing Results & Vendor Ratings Not peer-reviewed
Finnrick lists 3,694 retatrutide tests from 256 vendors, dated Dec 17, 2024 to Aug 26, 2026; its public test history table shows only 200 of them.
- The peptide problem: Hype is outrunning the evidence
McMaster professor Stuart Phillips writes that the "third-party" labs issuing peptide purity certificates are often the vendors themselves, linking to a CBC Radio explainer.
- Why Endotoxin Testing Matters for Peptides Not peer-reviewed
Of 140 Finnrick endotoxin tests, nearly 63% found none, 29% found traces below the limit of quantification, and nearly 8% found amounts above that limit.
Reporting and emergency help
- 9-1-1 Services for Traditional Wireline, VoIP and Wireless Phone Services
Explains how 9-1-1 calls work in Canada and gives tips for making an emergency call, such as telling the operator the nature and location of the emergency.
- Canada Vigilance Program
Describes Health Canada's side effect monitoring program, says reports can be made online, by phone, fax, or mail, and lists its phone line, 1-866-234-2345.
- Centres
Lists Canada's five regional poison centers, open 24 hours a day, 7 days a week, and the phone numbers to call from each province and territory.
- Contact OCI
Lists the address and phone number of FDA's Office of Criminal Investigations and links to the FDA form for telling law enforcement about an issue.
- Counterfeit (fake) medicines and medical devices
Explains the risks of counterfeit medicines and lists ways to report a suspected fake, including an online form and the free-call line 1800 020 653.
- NHTSA's National 911 Program
Confirms 911 as the number to call immediately in an emergency and warns that the website itself cannot provide emergency help.
- Poison Help
Gives the toll-free Poison Help line, 1-800-222-1222, available 24/7, which connects callers to their local poison center.
- Poisoning
Gives the Poisons Information Centre number, 13 11 26, which you can call 24 hours a day from anywhere in Australia, and says when to call triple zero (000).
- Report a perceived breach or questionable practices
Online form to report counterfeit products or someone supplying an unapproved therapeutic product; reporters can use a pseudonym or stay anonymous.
- Report a problem to the FDA
Online form to report harm, product quality or mislabeling issues, or insider information about an FDA-regulated product; it takes 5 to 10 minutes.
- Report a side effect
Says anyone can report a side effect to a health or cannabis product and lets the reader pick a product type to start a report.
- Reporting adverse events for consumers
Lets consumers report a medicine or vaccine side effect online through the Adverse Event Management System and links to the form for reporting fake medicines.
- Reporting Serious Problems to FDA
Lets consumers report a serious reaction or product quality problem to MedWatch online, on Form FDA 3500B, or by calling 1-888-INFO-FDA and pressing 2.
- Triple Zero
Says to call Triple Zero (000) if someone is seriously injured, in danger, or needs urgent help, and notes that the calls are free.
- webPOISONCONTROL: Your Online Poison Control
Lets a reader enter details of a possible poisoning and get a free, confidential recommendation online; it sends serious cases to 911 or a poison center.
- What to report to the Yellow Card scheme
Explains that the public and health professionals can report side effects, defective products, and falsified or fake healthcare products to the Yellow Card scheme.
- When to use NHS 111 online or call 111
Explains when to use 111 online or call 111 for urgent medical help, and says to call 999 or go to A&E in an emergency.